| BURU 0.2231 0.86% | PLUG 3.81 34.63% | ASNS 0.6247 68.84% | DFLI 1.89 76.64% | CHR 0.1609 22.64% | OPEN 8.11 1.25% | SOXS 4.69 1.96% | BNAI 0.6015 69.44% | TSLL 19.63 -2.92% | RKT 17.8 -3.10% | LAC 9.04 31.78% | SNAP 8.54 3.89% | RGTI 40.06 13.16% | NVDA 187.62 -0.67% | TSLA 429.83 -1.42% | CAN 1.31 -0.76% | INTC 36.83 -1.26% | SQQQ 15.05 1.42% | DNN 2.8 1.08% | QUBT 24.62 23.22% | PSLV 16.13 2.35% | GPUS 0.54 11.57% | ACHR 11.57 13.65% | PLTR 173.07 -7.47% | RR 6.18 19.77% | F 12.67 3.68% | QBTS 32.7 11.95% | BBAI 7.19 -1.10% | TLRY 1.62 0.62% | TSLQ 8.51 2.78% | IBIT 69.81 1.51% | SOFI 25.24 -2.81% | AAL 11.58 1.31% | IONZ 3.4 -11.92% | QS 15.92 11.33% | SOUN 17.85 0.06% | DVLT 1.34 -12.42% | ONDS 9.91 7.60% | PFE 27.37 1.07% | SOXL 38.23 -2.18% | CIFR 14.7 6.44% | SPY 669.21 0.00% | HIVE 4.45 2.06% | CJET 0.169 -0.59% | BITF 3.01 2.73% | BBD 3.17 0.11% | SHOT 0.3702 31.74% | ANRO 6.89 56.24% | NIO 7.7 -2.41% | MARA 18.82 0.16%
Article image

MoonLake Immunotherapeutics (NASDAQ: MLTX) Faces Challenges Amid Disappointing Trial Results

MoonLake Immunotherapeutics (NASDAQ: MLTX) is a biopharmaceutical company focused on developing innovative treatments for inflammatory diseases. Recently, Jefferies set a price target of $8 for NASDAQ:MLTX, suggesting a potential price increase of about 32.97% from its current price of $6.02. This comes amid significant challenges for the company.

RBC analysts have drastically reduced their target price for MLTX from $67 to $10 per share, following disappointing trial results for sonelokimab, a treatment for skin disease. The stock was downgraded from ‘Outperform’ to ‘Sector Perform’ due to a reduced market opportunity and the need for further clarity, as highlighted by RBC.

The trial results showed sonelokimab's effectiveness ranged between 9-17%, which is not competitive with existing treatments. Despite this, RBC analysts see potential for the drug, estimating it could be sold for around $1 billion if regulatory approval and future data are favorable.

Following these developments, MLTX shares have dropped over 90%, trading at $6.08. The Phase 3 VELA-1 and VELA-2 trials, which enrolled 838 patients, assessed the efficacy of sonelokimab using HiSCR75 as the primary endpoint. The trials compared a 120mg dose of sonelokimab to a placebo.

Currently, MLTX is priced at $6.25, having decreased by approximately 89.93% from its 52-week high of $62.75. The stock has fluctuated between $5.96 and $7.13 today, with a market capitalization of about $396.57 million and a trading volume of 78.42 million shares.

Published on: September 29, 2025